Longevity biotechnology and AI for biology, plus open-source tools for AI agents.
199 Biotechnologies researches partial cellular reprogramming and senolytics, and builds the AI and software behind the 199 group's research, diagnostics and clinical care. Boris Djordjevic founded it in 2022; we work from London and Singapore.
We open-source the tools we build for that work: Claude Code skills, MCP servers, Rust command-line tools for AI agents, and machine-learning models that run on Apple Silicon.
| Project | What it does |
|---|---|
| claude-deep-research-skill | Deep research for Claude Code: a multi-stage pipeline with source scoring, citation tracking and automated validation. Our most-starred repository. |
| whatsrust | WhatsApp in pure Rust for AI agents: one 5 MB binary, 54 API endpoints and 30 MCP tools. |
| engram | Persistent memory for AI agents: hybrid BM25, semantic and knowledge-graph search, local-first. |
| ritalin | Proof-carrying completion for coding agents: blocks "done" until every critical requirement has evidence. |
| lhm-foundational-model | Health-trajectory prediction from longitudinal records, comparing Transformer, Mamba and continuous-time architectures. |
| search-cli | Web search for AI agents: 13 providers rank-fused in one Rust binary. |
- motion-dev-animations-skill: Motion.dev web animations with spring physics, scroll effects and gestures.
- claude-skill-seo-geo-optimizer: search and generative-engine optimisation for web content.
- swiftui-claude-skills and app-store-connect-skill: iOS 26 interfaces and App Store Connect from the terminal.
- context-priming: builds a coding agent's context before the first token.
- autoresearch-cli: an autonomous experiment loop that runs overnight with any coding agent.
- agent-cli-framework: Rust CLIs that agents can discover and call without an MCP server.
- 199-mcp: MCP servers, including biological age from blood biomarkers (PhenoAge) and ElevenLabs voice agents.
- nemotron-asr-mlx: NVIDIA Nemotron streaming speech recognition on MLX.
- textstream-asr: live speech-to-text with Qwen3-ASR and Silero VAD.
- ultrashape-mac and stream-diffvsr: 3D shape generation and video super-resolution on Apple GPUs.
- sequence-optimiser: CpG-depleted, codon-optimised FST344 follistatin sequences for AAV gene therapy.
Peer-reviewed work by our founder, including:
- Tunable hydrogel-based micropillar arrays for myelination studies. Nature Methods (2026). doi
- Emergent mechanical control of vascular morphogenesis. Science Advances (2023). doi
- Longevity biotechnology: bridging AI, biomarkers, geroscience and clinical applications for healthy longevity. Aging (2024). doi
All eight papers: borisdjordjevic.com/publications
| Account | What lives there |
|---|---|
| 199-biotechnologies | Skills, agent tools and models (this page) |
| paperfoot | Paperfoot AI's Rust CLIs for agents, with a Homebrew tap |
| 199-mcp | MCP servers |
| longevityboris | Boris Djordjevic's personal projects |
Built by Boris Djordjevic at 199 Biotechnologies and Paperfoot AI | borisdjordjevic.com
199 Biotechnologies (SG) Pte Ltd · 199.bio
