Issues

• Why are they different?

  MRCIEU/TwoSampleMR#662 · Filter by author yikeshu0611 opened on Dec 10, 2025
  9

  

• mv_extract_exposures runs too slow when the number of instruments is large

  MRCIEU/TwoSampleMR#637 · Filter by author ruoyao-shi opened on Jun 20, 2025

• [Suggestion]: Add parameters for which methods to use and add to the output mr_report()

  enhancement
  MRCIEU/TwoSampleMR#636 · Filter by author james-edward-hart opened on Jun 17, 2025

• mr_ruckers missing correction for underdispersion leads to p-values = 0

  MRCIEU/TwoSampleMR#630 · Filter by author arendma opened on May 14, 2025

• Difference between mv_multiple(instrument_specific = TRUE) and regular pairwise MR?

  MRCIEU/TwoSampleMR#628 · Filter by author mooreann opened on May 12, 2025

• [BUG]: The se function for Wald ratio test in mr.R is wrong

  bug
  MRCIEU/TwoSampleMR#614 · Filter by author Yining97 opened on Mar 28, 2025
  1

• steiger_pval is NaN

  MRCIEU/TwoSampleMR#585 · Filter by author amaa11 opened on Jan 22, 2025
  1

• mv_extract_exposures_local possibility to include a dataframe already clumped

  enhancement
  MRCIEU/TwoSampleMR#569 · Filter by author AngeTKL opened on Oct 2, 2024

• [BUG]: Error in mv_extract_exposures_local()

  bug
  MRCIEU/TwoSampleMR#562 · Filter by author trprice08 opened on Sep 23, 2024
  1

• [BUG]: P value and 95% CI doesn't match

  bug
  MRCIEU/TwoSampleMR#558 · Filter by author Yvonnehuang1316 opened on Sep 4, 2024

• add.rsq[BUG]:

  bug
  MRCIEU/TwoSampleMR#445 · Filter by author docliu94 opened on Oct 18, 2023

• [BUG]: ld_matrix run locally does not align alleles to 1000G phase 3 reference data

  bug
  MRCIEU/TwoSampleMR#420 · Filter by author JonnyBaseball opened on Jun 14, 2023
  2

• Add extra MR Steiger sensitivity

  enhancement
  MRCIEU/TwoSampleMR#418 · Filter by author explodecomputer opened on Jun 12, 2023
  

• [BUG]: setting pop explicitly

  bug
  MRCIEU/TwoSampleMR#411 · Filter by author MatthewOGoodman opened on May 4, 2023

• Finding proxy SNPs in the outcome data when using the "read_outcome_data" function.

  enhancement
  MRCIEU/TwoSampleMR#407 · Filter by author nicholaspudjihartono opened on Apr 19, 2023
  2

• [BUG]: MR_forest_plot display all SNPs, and no way to change

  bug
  MRCIEU/TwoSampleMR#386 · Filter by author jielab opened on Oct 24, 2022

• [BUG]: mr_egger_regression

  bug
  MRCIEU/TwoSampleMR#379 · Filter by author yitangsun opened on Aug 22, 2022

• [BUG]: mr_ivw_mre

  bug
  MRCIEU/TwoSampleMR#377 · Filter by author yitangsun opened on Aug 19, 2022

• Improved Column-name Error Check would avoid much user pain

  enhancement
  MRCIEU/TwoSampleMR#376 · Filter by author MatthewMaher opened on Aug 11, 2022

• Direction of MR beta requires more documentation about the exposure and outcome.

  enhancement
  MRCIEU/TwoSampleMR#373 · Filter by author mocksu opened on Jul 25, 2022

• [BUG]: GTEx-MR error: The following required columns are missing from outcome

  bug
  MRCIEU/TwoSampleMR#356 · Filter by author Shicheng-Guo opened on Jun 13, 2022
  1

• sort_1_to_many() additional sort_action option

  enhancement
  MRCIEU/TwoSampleMR#352 · Filter by author db15954 opened on May 31, 2022

• combine_all_mrresults[BUG]:

  bug
  MRCIEU/TwoSampleMR#350 · Filter by author db15954 opened on May 26, 2022

• Possible incorrect data related to HbA1c (Soranzo N, MAGIC, 2010) and fasting glucose (Dupuis J, MAGIC, 2010)[BUG]:

  bug
  MRCIEU/TwoSampleMR#335 · Filter by author jamesliu0501 opened on Dec 8, 2021

• mv_multiple results

  MRCIEU/TwoSampleMR#327 · Filter by author syuxuan opened on Oct 26, 2021